Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes
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چکیده
منابع مشابه
Evaluating the effects of galbanic acid on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes
Objective: Ferula szowitsiana has been widely used for medicinal purposes around the world. The anti-oxidant effect of F.szowitsiana had been proved. The current study aims to determine the protective effects of galbanic acid, a sesquiterpene coumarin from F. szowitsiana, against hydrogen peroxide (H2O2) - induced oxidative DNA damage in human lymphocytes. Materials and Methods: Human lymphocyt...
متن کاملevaluating the effects of galbanic acid on hydrogen peroxide-induced oxidative dna damage in human lymphocytes
objective: ferula szowitsiana has been widely used for medicinal purposes around the world. the anti-oxidant effect of f.szowitsiana had been proved. the current study aims to determine the protective effects of galbanic acid, a sesquiterpene coumarin from f. szowitsiana, against hydrogen peroxide (h2o2) - induced oxidative dna damage in human lymphocytes. materials and methods: human lymphocyt...
متن کاملVitamin C and Oxidative DNA Damage Revisited
Reactive oxygen metabolites can pro mote carcinogenesis by damaging DNA. vi tamin C is a redox chemical with antioxi dant and pro-oxidant properties that may produce radical species depending on the presence of various conditions. Nevertheless, evidence presented herein discourages the consideration of any mutagenic or carcino genic activity of vitamin C. In contrast, it substantiates a pro...
متن کاملEffects of smoking and aging on oxidative DNA damage of human lymphocytes.
The effects of H2O2-induced oxidative DNA damage in 80 healthy individuals with relation to age (20-25 and 55-60 years old) and smoking has been investigated with the comet assay technique. Both factors have shown a significant effect upon basal DNA damage with smoking appearing to have the most impact. A differentiation of the four groups response to induced oxidative damage was also observed....
متن کاملThe effect of vitamin C or vitamin E supplementation on basal and H2O2-induced DNA damage in human lymphocytes.
There is a wealth of epidemiological information on antioxidants and their possible prevention of disease progression but very little of the research on antioxidants has involved intervention studies. In this study, the potential protective effect of vitamin C or E supplementation in vivo against endogenous and H2O2-induced DNA damage levels in lymphocytes was assessed. The supplementation invo...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 1998
ISSN: 0002-9165,1938-3207
DOI: 10.1093/ajcn/67.6.1210